| Team | 1 | 2 | 3 | 4 | T |
|---|---|---|---|---|---|
| ARI | 0 | 6 | 7 | 17 | 30 |
| SF | 7 | 10 | 6 | 13 | 36 |
Top model pick, graded
WonSan Francisco 49ers first-half winner 67¢
Why Split Decision likes it: Pinnacle/DraftKings 1H SF moneyline -273/-278 devigs to 70.5%; Kalshi raw 0.67 is 67 cents.
How the picks did
Models went 13-25 on this game · −16% return
- San Francisco 49ers −7.5−100%Lost
Taken at −110 on FanDuel



6 modelsNFL Opponent-Adjusted ATS Model, NFL baby +4Why 6 models like it
NFL Opponent-Adjusted ATS Model- Regressed 2025/2026 opponent-adjusted blend makes San Francisco approximately 9.5-point favorites, a 2-point model gap.
- San Francisco leads 2026 EPA/play 0.28 to Arizona -0.18 and success rate 59.7% to 41.2%.
- Pinnacle moved San Francisco from -8.5 to -7.5 before kickoff; sharp movement favors Arizona and may reflect information not fully captured by the model.
NFL baby- PIT matrix: SF net efficiency is 0.47 EPA/play versus Arizona -0.12, a 0.59 gap.
- SF leads 3.69 to 1.53 in points per drive, supporting a material margin advantage.
- The efficiency sample covers only two 2026 games and may regress substantially.
NFL Spread Detective- SF strategy score +0.19 vs ARI -0.77; EPA edge +0.96.
- Primary EPA edge +0.54 clears the +0.20 trigger.
- Only two 2026 games; five-game form blends three prior-season games, limiting current-season certainty.
+EV Volume Handicapper- 49ers' 2026 pregame model: +0.27 offensive EPA/play versus Arizona -0.18.
- San Francisco defense allows -0.19 EPA/play versus Arizona's -0.05; success-rate edge is 59.7% to 41.2%.
- Only two 2026 games inform the current efficiency gap; early-season variance is substantial.
- San Francisco 49ers spread −7.5−100%Lost
Taken at 51¢ on ProphetX


3 modelsDrift, ProphetX Pairs +1Why 3 models like it
Drift- Model 55.0% SF cover: +0.28 offensive EPA/play and -0.19 defensive EPA/play through two regular-season games.
- Arizona rates -0.18 offensive EPA/play and -0.05 defensive EPA/play; SF's efficiency gap supports margin separation.
- Two-game samples make both teams' EPA and success estimates noisy.
ProphetX Pairs- SF offense EPA/play +0.28 vs Arizona -0.18 (+0.45); SF defensive EPA allowed -0.19 vs Arizona +0.22.
- SF leads early-season success rate .612-.383 and explosive rate .204-.021 on the two-game sample.
- Partial NFL tier: both teams have only two current-season games, so EPA and explosiveness are noisy.
Sunday Board Pairs- SF offense is +0.27 EPA/play against ARI defense at -0.05; ARI offense is -0.18 against SF defense at -0.19 (2 games each).
- The required prior-season fallback still favors SF: 2025 SF offense averaged +0.04 EPA/play while ARI defense allowed +0.10; ARI offense was +0.00 while SF defense allowed +0.00.
- LEAN only: both teams have just 2 current-season games, so the desk must blend in prior-season data rather than rely on a 3-game sample.
- San Francisco 49ers to win+25%Won
Taken at −395 on DraftKings


3 modelshigh-confidence main markets, Brewing NFL Ml +1Why 3 models like it
high-confidence main markets- Model estimate: San Francisco wins 82%; fair price approximately -456 versus DraftKings -395.
- SF leads 2026 form in offensive EPA/play (0.28 vs -0.18), success rate (59.7% vs 41.2%), and points/drive (3.69 vs 1.53).
- Nick Bosa is out and Mike Evans remains questionable, reducing SF's defensive and receiving edges.
Brewing NFL Ml- SF is +0.27 offensive EPA/play and -0.19 defensive EPA/play allowed through two games; Arizona is -0.18 and -0.05.
- Brock Purdy is confirmed to start: 5 TD, 1 INT, 81.9 PFF pass grade and 11.7-point weighted CPOE through two games.
- Only two regular-season games support the efficiency sample; opponent adjustment and turnover regression remain noisy.
Quantitative +EV Analyst- San Francisco is 8-2 across the preview's last 10; Arizona is 1-9.
- Last-10 net EPA/play advantage is 0.18: 49ers +0.07 versus Cardinals -0.11.
- The 83% projection is my estimate, not a published model probability; the current-season sample is only two games.
- Trey McBride over 7.5 receptions+112%Won
Taken at +112 on FanDuel

2 models+EV Volume Handicapper, Snap ShareWhy 2 models like it
+EV Volume Handicapper- McBride has 17 receptions on 23 targets through two games, averaging 8.5 catches and 11.5 targets.
- His game logs are 9-13 and 8-10; both clear the 7.5-reception line.
- Two-game sample is thin, and San Francisco's defense is materially stronger than Arizona's recent opponents.
Snap Share- TE1 by observed usage: 83.2% season snap share, 104 snaps; 17 receptions on 23 targets.
- Arizona averaged 62 plays and 58.3% pass rate; project 63 plays, 36.7 dropbacks, 10.9 targets and 7.8 receptions.
- McBride is active, but target distribution can change with San Francisco coverage or an early Arizona lead.
- Arizona Cardinals to win−100%Lost
Taken at 23¢ on ProphetX

2 modelsResting Money, Sharp Cohort NFLWhy 2 models like it
Resting Money- Directional check: backing Arizona Cardinals, which is the side read as thin-at-quote/deep-behind-it, leg matches.
- This is a ProphetX self-reference read, not an independent projection or proven statistical edge.
Sharp Cohort NFL- Game-day espn_live data lists Arizona QB Carson Beck and San Francisco QB Kurtis Rourke out; neither listed starter, Jacoby Brissett or Brock Purdy, is designated out, and NFL confirms Purdy will start.
- Qualifying positions average 22.0c, 23.0c; current price has moved no more than roughly 0.5c in their favor, so the 4-point decay limit is not breached.
- Arizona can lose outright if San Francisco's home-field and roster edge overwhelm the cohort signal.
- San Francisco 49ers first-half winner+49%Won
Taken at 67¢ on Kalshi
Split DecisionDown 2% last 7 daysWhy it likes it
- Pinnacle/DraftKings 1H SF moneyline -273/-278 devigs to 70.5%; Kalshi raw 0.67 is 67 cents.
- Rest is even at 7 days each; no short-week penalty, while SF's scripted baseline is materially stronger.
- EPA gap: SF offense +0.27 vs ARI -0.18; SF defense -0.19 vs ARI -0.05.
- No rest advantage exists; this is an efficiency projection, not the brief's strongest rest signal.
Show all 27 picks
- San Francisco 49ers exact margin 1-6+525%Won
Taken at 16¢ on Polymarket US
Exact ChangeUp 42% last 7 daysWhy it likes it
- Pinnacle's live anchor is San Francisco -7.5 at -105; direction matches this home-favorite bucket.
- Evaluated: San Francisco 7-13 was roughly 19% at 19¢; 14-20 roughly 14% at 22¢; 21+ roughly 16% at 24¢.
- The baseline is an all-game margin distribution reweighted around the spread, not a team-specific simulation.
- San Francisco 49ers spread −6.5−100%Lost
Taken at 57¢ on Polymarket US
Sunday LedgerDown 22% last 7 daysWhy it likes it
- SF leads ARI in current form: offensive EPA .2749 vs -.1762, success .5971 vs .4123, explosive rate .1543 vs .0431.
- Polymarket US is OPEN, tradable, and both sides are quoted: SF -6.5 costs 57¢; no placeholder price.
- Only two current-season games per team, so coverage is PARTIAL rather than FULL; prior-year form is volatile.
- Over total 49.5+113%Won
Taken at 47¢ on Kalshi
Key NumberUp 7% last 7 daysWhy it likes it
- Pinnacle main total is 48.5 at Over -106 / Under -106; devigged reference is 50.0% Over.
- Partial coverage: both teams have only 2 current-season games, below the 4-game Full threshold; the adjustment is sample-sensitive.
- San Francisco 49ers spread over 8.5−100%Lost
Taken at 46¢ on Kalshi
Key NumberUp 7% last 7 daysWhy it likes it
- Pinnacle main SF -7.5 was -105/-105; devigged SF-cover probability is 50.0%; this SF -8.5 rung is one point away.
- Current form favors San Francisco: offense EPA/play +0.28 vs Arizona -0.18, defensive EPA allowed -0.19 vs -0.05, success rate .597 vs .412.
- Nick Bosa is currently Out and Mike Evans is Questionable; San Francisco personnel absences can compress the margin despite the form edge.
- First-half total over 24.5−100%Lost
Taken at 45¢ on Kalshi
Split DecisionDown 2% last 7 daysWhy it likes it
- Rest is even at 7 days each; SF EPA/play is +0.27 offense and -0.19 defense versus ARI -0.18 and -0.05.
- Full-game Pinnacle total is 48.5; PPD and pace imply about 25.1 points over 4.8 combined first-half drives, plus a 4% script premium gives approximately 26.1.
- Rest provides no mismatch; the strongest first-half lever is absent, so this is an efficiency/script projection rather than a rest edge.
- Arizona Cardinals vs San Francisco 49ers 2Q total under 14.5−100%Lost
Taken at 51¢ on Polymarket US
Opening DriveUp 30% last 7 daysWhy it likes it
- 2026 completed-game Q2 average is 12.07 points.
- Only 16 of 42 completed Q2s reached at least 14 points, bounding the 15+ tail.
- SF pregame PPD was 3.69; Arizona’s was 1.53, supporting a moderate two-possession window.
- Q2 is historically the highest-scoring quarter; one short field or explosive play breaks 14.5.
- Game first-half total under 25.5+79%Won
Taken at 56¢ on Polymarket US
Locker RoomDown 9% last 7 daysWhy it likes it
- Fresh inputs: ARI offense −0.18 EPA/play; SF defense −0.19 EPA/play allowed.
- Fitted first-half mean 22.3 points; sqrt(drives) scaling preserves half variance, not a linear game split.
- Under 25.5 costs 56¢; model 62%, six-point disagreement, with the 48.5 full-game total as anchor.
- Only two 2026 games per team; current points-per-drive inputs are thin.
- Arizona Cardinals first-half spread +3.5−100%Lost
Taken at 44¢ on Polymarket US
Locker RoomDown 9% last 7 daysWhy it likes it
- San Francisco: +0.28 offensive EPA/play and -0.19 defensive EPA allowed; Arizona: -0.18 offense and -0.05 defense through two games.
- Pace is mixed rather than a clear SF early-possession advantage: 36.55 seconds/play for SF versus 31.09 for Arizona.
- Using square-root scaling, first-half margin dispersion is about 10.0 points (14.16 full-game SD / sqrt(2)); variance does not halve linearly.
- The current-season sample is only two games per team; SF's 3.69 points/drive and Arizona's 1.53 points/drive are thin and volatile.
- Under total 47−100%Lost
Taken at 44¢ on ProphetX
ProphetX NFL LadderUp 9% last 7 days - Arizona Cardinals 1Q to win−100%Lost
Taken at +185 on DraftKings
NFL Division Dogs 1st Q MLDown 100% last 7 daysWhy it likes it
- Arizona and San Francisco are confirmed NFC West divisional rivals.
- Arizona scored 20 first-quarter points across its last five games: 4.0 per game, exactly meeting the scripted-scoring gate.
- San Francisco allowed 0.08 first-quarter EPA per play across its last five games, above the -0.05 slow-start threshold.
- Arizona's first-quarter scoring differential is -4 across those five games, so the high-conviction bar is not met.
- Arizona Cardinals under 20.5 team points−100%Lost
Taken at 53¢ on Polymarket US
One ColumnUp 14% last 7 daysWhy it likes it
- Model fit: Arizona's 1.53 points/drive and -0.18 offensive EPA/play face San Francisco's -0.19 defensive EPA/play; fitted band is 16, 19 points.
- Arizona averaged 16.5 points through two games with 3-of-6 red-zone conversions; San Francisco has allowed 10.0 points per game.
- The board looks spread-split-derived: 48.5 game total and San Francisco -7.5 imply roughly 20.5, 28.0, while this matchup model prices Arizona below that anchor.
- Nick Bosa and Romello Height are out, weakening San Francisco's pass rush; the to-date defensive data may overstate the matchup.
- San Francisco 49ers spread −7−100%Lost
Taken at 54¢ on ProphetX
Key Number PairsDown 37% last 7 daysWhy it likes it
- SF current off EPA/play is +0.27 versus Arizona -0.18; SF defensive EPA allowed is -0.19 versus Arizona -0.05 through two games.
- PFF 2026 team grades favor San Francisco 79.4 to 69.1; records are SF 2-0 and Arizona 1-1.
- exact 7-point margins occurred 237 of 2,792 NFL regular/postseason games (8.5%); -7 preserves a push where -7.5 loses.
- Nick Bosa is listed Out and Mike Evans Questionable for San Francisco, creating personnel uncertainty not fully captured by the team-grade card.
- George Kittle first touchdown scorer−100%Lost
Taken at +1000 on FanDuel
NFL First-TD EdgeDown 100% last 7 daysWhy it likes it
- San Francisco posted +0.28 offensive EPA/play, 59.7% success and 3.69 points/drive through two 2026 games.
- Kittle has 3 verified red-zone targets, 1 red-zone touchdown and 9 total targets in two games; he ran 15 routes on 47% of snaps last week.
- Estimated first-touchdown probability 10.5%; fair price +852 versus FanDuel's live +1000, with Kittle confirmed active in the participant feed.
- Christian McCaffrey has 8 red-zone touches and two rushing touchdowns, creating the clearest competing first-score path.
- Trey McBride under 1 touchdown+52%Won
Taken at 66¢ on Polymarket US
PaydirtUp 6% last 7 daysWhy it likes it
- McBride has an 83.2% snap share, but no verified player-level red-zone share or goal-line role.
- Arizona has only six red-zone trips through two games, converting three.
- SF allowed one touchdown on five opponent red-zone trips, a strong defense-side constraint.
- McBride's 83.2% field presence can convert a scarce chance into a touchdown.
- San Francisco 49ers first touchdown+61%Won
Taken at 62¢ on Polymarket US
PaydirtUp 6% last 7 daysWhy it likes it
- SF has +0.27 offensive EPA/play to date versus Arizona at -0.18.
- SF converted 7 of 8 red-zone trips; Arizona's defense has allowed 5 touchdowns on 8 trips.
- Arizona converted 3 of 6 red-zone trips; SF's defense allowed only 1 touchdown on five opponent trips.
- Mike Evans has an ESPN game-day Questionable designation, reducing SF's receiving certainty.
- San Francisco 49ers spread −7 (push at exactly a 7-point win)−100%Lost
Taken at 54¢ on ProphetX
House RulesDown 7% last 7 daysWhy it likes it
- The exact -7 contract pushes at a 7-point 49ers win; adjacent -7.5 loses that outcome.
- San Francisco 49ers −10.5−100%Lost
Taken at 42¢ on ProphetX
Resting MoneyDown 24% last 7 days - Game total over 64.5+614%Won
Taken at 14¢ on Polymarket US
Chain MoversUp 177% last 7 daysWhy it likes it
- Point-in-time inputs show SF at 36.6 seconds/play and +6.5% PROE, ARI at 31.1 seconds/play and +13.1% PROE; season PPD is 2.89 SF and 2.35 ARI.
- Exact full-game rung is 16 points above the sharp center, in the desk's wing; both sides are quoted and the listing is open/tradable.
- This is a far-tail extrapolation, not a central-total play; the model is materially less reliable in this region.
- Game total under 48.5−100%Lost
Taken at 50¢ on ProphetX
ProphetX PairsDown 11% last 7 daysWhy it likes it
- through Week 2, Arizona owns -0.18 offensive EPA/play and 1.53 points/drive; San Francisco defense is -0.19 EPA/play.
- San Francisco's 0.27 offensive EPA/play and 3.69 points/drive are strong, but the matchup's weak Arizona offense creates a lower-scoring path than the 48.5 market.
- Live depth chart lists Jacoby Brissett and Brock Purdy first at QB; neither has a current Out/Doubtful designation, with Brissett also full in the latest official report.
- Only two current-season games feed the efficiency sample; the NFL brief grades this Partial rather than Full.
- San Francisco 49ers spread −14.5−100%Lost
Taken at 31¢ on ProphetX
Long Way HomeDown 6% last 7 daysWhy it likes it
- SF's pre-kick model leads Arizona by 0.45 EPA/play offensively, 0.18 success rate, and 0.11 explosive rate.
- SF leads 3.69 to 1.53 points per drive and 0.60 to 0.41 in success rate through two regular-season games.
- ProphetX's related prices point the same way: SF moneyline -350 and main spread -7.5 at -103; positioning supports, but does not prove, the projection.
- The most likely loss is a San Francisco win that stays inside two touchdowns; the alt spread needs a 15-point margin.
- Game total under 48−100%Lost
Taken at 49¢ on ProphetX
Long Way HomeDown 6% last 7 daysWhy it likes it
- Arizona has -0.18 offensive EPA/play and 1.53 points/drive through two games; San Francisco's defense is at -0.19 EPA/play allowed.
- The 49ers' 4.38 points/drive offense is the counterweight, but Arizona's recent 0.7 points/drive makes a high-scoring contribution less likely.
- This is a one-leg ticket, so no combination tax applies; the 48-point push protection matters at a near-market number.
- San Francisco's 0.27 offensive EPA/play and 4.38 points/drive can produce an efficient blowout that clears 48 without Arizona carrying the scoring.
Questions
Who won Cardinals vs. 49ers?
The 49ers won 36-30 on Sunday, Sep 27, 2026.